Perspectives Series: Molecular Medicine in Genetically Engineered Animals Biological Insights through Genomics: Mouse to Man

Series Editor, Kenneth R. Chien January 1 Gene modification via “plug and socket” gene targeting................................. Jada Lewis, Baoli Yang, Biological insights through genomics: mouse to man ..................................... Pete Detloff, and Oliver Smithies January 15 Biological insights through genomics: mouse to man ..................................... Edward M. Rubin and Gregory S. Barsh February 1 In vitro differentiation of murine embryonic stem cells: new approaches to old problems .................................................................... Mitchell J. Weiss and Stuart H. Orkin February 15 Genes and physiology: molecular physiology in genetically engineered animals......................................................................................... Kenneth R. Chien March 1 Animal models of human disease for gene therapy........................................ James M. Wilson March 15 Targeted mutagenesis: analysis of phenotype without germline transmission.................................................................................................... Andras Nagy and Janet Rossant April 1 Transgenesis in the rat and larger mammals.................................................. John Mullins and Linda Mullins April 15 Zebrafish: heritable diseases in transparent embryos .................................... Mark Fishman and Wolfgang Driever May 1 Recent advances in conditional gene mutation by site-directed recombination............................................................................. Jamey Marth and Klaus Rajewsky